Search Result
Results for "
thermal threshold,?hyperalgesia
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
4
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N6875
-
|
Others
|
Metabolic Disease
|
oleuropeinic acid is present initially in olive tissues or formed by the thermal treatment, possibly by the oxidation of oleuropein. Oleuropeinic acid is an antioxidant-soluble fiber .
|
-
-
- HY-W248115
-
|
Fluorescent Dye
|
Others
|
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .
|
-
-
- HY-151771
-
|
ADC Linker
|
Others
|
DACN(Tos,Mal) is a click chemistry reagent containing an azide. DACN(Tos,Mal) possess high thermal and chemical stability along with comparable click reactivity .
|
-
-
- HY-152469
-
|
Epigenetic Reader Domain
|
Cancer
|
Eleven-Nineteen-Leukemia Protein IN-1 is an inhibitor of ENL YEATS domain with an IC50 value of 14.5 nM. Eleven-Nineteen-Leukemia Protein IN-1 interacts with ENL protein and enhances the thermal stability of ENL protein in vitro .
|
-
-
- HY-103177
-
|
Adenosine Receptor
|
Inflammation/Immunology
|
PSB-10 hydrochloride is a potent and selective antagonist of human adenosine A3 receptor (A3AR), with a Ki of 0.44 nM. PSB-10 hydrochloride shows more than 800-fold selectivity for hA3 over rA1, rA2A, hA1, hA2A and hA2B receptors (Ki=805, 6040, 1700, 2700, 30000 nM, respectively). PSB-10 hydrochloride produces thermal hyperalgesia in mice .
|
-
-
- HY-131986
-
|
TRP Channel
|
Neurological Disease
Inflammation/Immunology
|
LASSBio-1135 (Compound 3a) is an orally active TRPV1 antagonist. LASSBio-1135 is an anti-inflammatory and analgesic compound. LASSBio-1135 inhibits moderately the human PGHS-2 enzyme activity (IC50 = 18.5 μM). LASSBio-1135 reverts the Capsaicin (HY-10448)-induced thermal hyperalgesia and reduces the carrageenan-induced rat paw edem .
|
-
-
- HY-D0877
-
|
Biochemical Assay Reagents
|
Others
|
TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH) .
|
-
-
- HY-D1915
-
|
Fluorescent Dye
|
Others
|
ATTO 390 is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy.
|
-
-
- HY-110099
-
|
CXCR
|
Inflammation/Immunology
|
(±)-NBI-74330 is a potent and selective CXCR3 antagonist. (±)-NBI-74330 not only reduces tactile and thermal hypersensitivity but also enhances the analgesic properties of morphine. (±)-NBI-74330 can reduce microglial cell activation, increase astroglial cell activation, and downregulate the expression of some CXCR3 ligands in a rat neuropathic pain model .
|
-
-
- HY-D1305
-
|
Fluorescent Dye
|
Others
|
ATTO 488 carboxylic acid is a new fluorescent label based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 carboxylic acid is a carboxylic acid derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
-
- HY-D1917
-
|
Fluorescent Dye
|
Others
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
-
-
- HY-D1929
-
|
Fluorescent Dye
|
Others
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
-
- HY-D1932
-
|
Fluorescent Dye
|
Others
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
-
- HY-D1933
-
|
Fluorescent Dye
|
Others
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
-
- HY-D1935
-
|
Fluorescent Dye
|
Others
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
-
-
- HY-D1939
-
|
Fluorescent Dye
|
Others
|
ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
|
-
-
- HY-D1946
-
|
Fluorescent Dye
|
Others
|
ATTO 590 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 alkyne is an alkyne derivative of ATTO 590 and can be used to label proteins or antibodies.
|
-
-
- HY-D1957
-
|
Fluorescent Dye
|
Others
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
-
- HY-D1959
-
|
Fluorescent Dye
|
Others
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
-
- HY-D1961
-
|
Fluorescent Dye
|
Others
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
-
- HY-D1993
-
|
Fluorescent Dye
|
Others
|
ATTO 647 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 647 NHS ester is an NHS ester derivative of ATTO 647 that can be used to label proteins or antibodies.
|
-
-
- HY-D1999
-
|
Fluorescent Dye
|
Others
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
-
- HY-D2001
-
|
Fluorescent Dye
|
Others
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
-
- HY-D2002
-
|
Fluorescent Dye
|
Others
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
-
- HY-D2014
-
|
Fluorescent Dye
|
Others
|
ATTO 565 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 alkyne is an alkyne derivative of ATTO 565 and can be used to label proteins or antibodies.
|
-
-
- HY-D2015
-
|
Fluorescent Dye
|
Others
|
ATTO 488 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 alkyne is an alkyne derivative of ATTO 488 and can be used to label proteins or antibodies.
|
-
-
- HY-153524
-
|
Fluorescent Dye
|
Others
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
-
- HY-D2016
-
|
Fluorescent Dye
|
Others
|
ATTO 565 cadaverine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 cadaverine is a cadaverine derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
-
- HY-D2019
-
|
Fluorescent Dye
|
Others
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
-
- HY-D2021
-
|
Fluorescent Dye
|
Others
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
-
- HY-D2026
-
|
Fluorescent Dye
|
Others
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
-
-
- HY-D2035
-
|
Fluorescent Dye
|
Others
|
ATTO 514 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 alkyne is an alkyne derivative of ATTO 514 and can be used to label proteins or antibodies.
|
-
-
- HY-D2038
-
|
Fluorescent Dye
|
Others
|
ATTO 550 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 alkyne is an alkyne derivative of ATTO 550 and can be used to label proteins or antibodies.
|
-
-
- HY-D2046
-
|
Fluorescent Dye
|
Others
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
-
- HY-D2047
-
|
Fluorescent Dye
|
Others
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
-
- HY-D2052
-
|
Fluorescent Dye
|
Others
|
ATTO 532 iodacetamid is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 iodacetamid is an iodoacetamide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
-
- HY-D2058
-
|
Fluorescent Dye
|
Others
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
-
- HY-D2059
-
|
Fluorescent Dye
|
Others
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
-
- HY-D2062
-
|
Fluorescent Dye
|
Others
|
ATTO 740 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 NHS ester is an NHS ester derivative of ATTO 740 that can be used to label proteins or antibodies.
|
-
-
- HY-D2063
-
|
Fluorescent Dye
|
Others
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
-
- HY-D2073
-
|
Fluorescent Dye
|
Others
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
-
- HY-D2074
-
|
Fluorescent Dye
|
Others
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
-
-
- HY-N6600
-
|
Others
|
Others
|
Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material .
|
-
-
- HY-101482
-
U75630
|
Others
|
Inflammation/Immunology
|
Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.
|
-
-
- HY-N9929
-
|
Others
|
Others
|
Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability .
|
-
-
- HY-P5874
-
|
Calcium Channel
|
Inflammation/Immunology
|
Myr-TAT-CBD3 is CRMP2-CaV2.2 interaction inhibitor. Myr-tat-CBD3 can significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity induced in a rat model of postoperative pain. Myr-TAT-CBD3 can be used to study inflammation and postoperative pain .
|
-
-
- HY-151754
-
|
ADC Linker
|
Others
|
DACN(Tos2,6-OH) is a click chemistry reagent containing an Azide. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. The reactivity of an alkyne heavily depends on the electronic and steric characteristics of the substituents as well as structural strain. In comparison to nonbent acyclic alkynes, cyclononyne alkynes show remarkably high reactivity. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. In comparison to cyclooctynes, DACNs possess high thermal and chemical stability along with comparable click reactivity . DACN(Tos2,6-OH) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-111029
-
|
GlyT
|
Neurological Disease
|
ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
|
-
-
- HY-103368
-
|
Chloride Channel
|
Neurological Disease
|
Eact is a selective and potent activator of TMEM16A, directly activates the TRPV1 channels in sensory nociceptors and produces itch, acute nociception and thermal hypersensitivity .
|
-
-
- HY-111029A
-
|
GlyT
|
Others
|
ALX-1393 TFA, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model .
|
-
- HY-W011831
-
3-(Benzyldimethylammonio)propane-1-sulfonate; PDA
|
Biochemical Assay Reagents
|
Others
|
NDSB-256 is a non-stain remover sulfabetaine. NDSB-256 prevents protein aggregation and promotes denaturation of chemically and thermally denatured proteins .
|
-
- HY-144220
-
-
- HY-N6600S
-
|
Isotope-Labeled Compounds
|
Others
|
Octadecane-d38 is the deuterium labeled Octadecane[1]. Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material[2].
|
-
- HY-148707
-
-
- HY-151794
-
|
ADC Linker
|
Others
|
DACN(Ms) (hydrochloride) (compound 1ba) is a click chemistry reagent containing cyclononyne alkyne. DCN(Ms) (hydrochloride) has high thermal stability, chemical stability, water solubility, and high reactivity for cycloaddition reactions .
|
-
- HY-N9929S
-
|
Isotope-Labeled Compounds
|
Others
|
Docosane-d46 is the deuterium labeled Docosane[1]. Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability[2][3].
|
-
- HY-W040263
-
TAPS Na
|
Biochemical Assay Reagents
|
Others
|
TAPS sodium is a biological buffer that protects the structural integrity of lysozyme bacteria and prevents them from thermal denaturation at high temperatures. A pKa of 8.1 for TAPS results in half-maximal connexin channel activity .
|
-
- HY-106841
-
R-75231; R88021
|
Others
|
Inflammation/Immunology
|
Draflazine (R-75231) is a ENT1 inhibitor. Draflazine (R-75231) completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia and the carrageenan inflammation model of thermal and mechanical hyperalgesia .
|
-
- HY-125830
-
|
Others
|
Others
|
ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes.
ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.
|
-
- HY-B0352B
-
(R)-Org3770; (R)-6-Azamianserin
|
5-HT Receptor
|
Neurological Disease
|
(R)-Mirtazapine ((R)-Org3770) is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4 .
|
-
- HY-147934
-
|
HDAC
Apoptosis
|
Cancer
|
HDAC8-IN-3 (compound P19) is a potent HDAC8 inhibitor with IC50 value of 9.3 μM and produces thermal stabilization. HDAC8-IN-3 has cytotoxicity and induces apoptosis in leukemic cell lines .
|
-
- HY-B0352A
-
(S)-Org3770; (S)-6-Azamianserin
|
5-HT Receptor
|
Neurological Disease
|
(S)-Mirtazapine ((S)-Org3770) is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2 .
|
-
- HY-E70308
-
|
Endogenous Metabolite
|
Others
|
Glucose isomerase is a glucose isomerase that catalyzes the reversible isomerization of D-glucose and D-xylose into D-fructose and D-xylulose, respectively. Glucose isomerase is thermally stable and can be used to produce fructose syrup at high temperatures above 90°C. Glucose isomerase is widely distributed in prokaryotes .
|
-
- HY-B0352BS
-
(R)-Org3770 d3; (R)-6-Azamianserin d3
|
Isotope-Labeled Compounds
5-HT Receptor
|
Neurological Disease
|
(R)-Mirtazapine-d3 is a deuterium labeled (R)-Mirtazapine. (R)-Mirtazapine is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4[1].
|
-
- HY-152471
-
|
Epigenetic Reader Domain
|
Cancer
|
Eleven-Nineteen-Leukemia Protein IN-3 is an orally active inhibitor of ENL YEATS domain with an IC50 value of 15.4 nM. Eleven-Nineteen-Leukemia Protein IN-3 down-regulates MYC expression through ENL in cells and can enhances the thermal stability of ENL protein in vitro .
|
-
- HY-131182
-
|
Sodium Channel
|
Neurological Disease
|
DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects .
|
-
- HY-W073183
-
|
Biochemical Assay Reagents
|
Others
|
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H 2PtCl 6·6H 2O and FeCl 2·4H 2O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .
|
-
- HY-B0352AS
-
(S)-Org3770 d3; (S)-6-Azamianserin d3
|
5-HT Receptor
|
Neurological Disease
|
(S)-Mirtazapine-d3 is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception.(S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].
|
-
- HY-W040201
-
3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
|
Biochemical Assay Reagents
|
Others
|
CHAPSO is a zwitterionic detergent that is thermally stable. CHAPSO is able to broaden the particle orientation distribution, enabling single-particle cryo-electron microscopy (cryo-EM) to produce isotropically uniform maps. CHAPSO can eliminate the directional bias of bacterial transcription complexes and help determine the structure of bacterial transcription complexes under cryo-electron microscopy .
|
-
- HY-P5802
-
|
Calcium Channel
|
Neurological Disease
|
ω-Conotoxin FVIA is an N-type Ca 2+channel (Ca v 2.2)
inhibitor. ω-Conotoxin FVIA reduces mechanical and thermal pain abnormalities
in a rat model of caudal nerve injury. ω-Conotoxin FVIA can be used in the
study of highly effective pain relievers with low side effects
.
|
-
- HY-151795
-
|
ADC Linker
|
Others
|
DACN(Tos) hydrochloride is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions, such strain-promoted azide-alkyne cycloadditions (SPAAC) by using cycloalkynes. DACNs possesses high thermal and chemical stability along with comparable click reactivity. DACN(Tos) hydrochloride can be used for the research of molecular conjugation .
|
-
- HY-144396
-
|
SHP2
Phosphatase
Akt
Apoptosis
|
Cancer
|
SHP2-IN-8 is a highly potent, selective, and cellularly active allosteric SHP2 inhibitor with IC50 value of 23 nM and Ki of 22 nM. SHP2-IN-8 is reversible and noncompetitive. SHP2-IN-8 causes a significant thermal shift with the ΔTm of 7.01 ℃. SHP2-IN-8 induces the apoptosis and inhibits the phosphorylation of AKT in Hela cells .
|
-
- HY-108298
-
PP 5; Perfluorodecahydronaphthalene
|
Others
|
Others
|
Perfluorodecalin liquids are largrly used in vitreoretinal surgery. Perfluorodecalin with tamponade lasting more than two days is detrimental to the retina in the case of rabbit. Perfluorodecalin can be used for the research of giant retinal tears . Perfluorodecalin is a non-toxic, non-flammable, thermally stable, non-bio-accumulating O2-carrier and used as artificial blood . Perfluorodecalin enhances bone regeneration and cell viability .
|
-
- HY-18618
-
|
Opioid Receptor
|
Neurological Disease
Inflammation/Immunology
|
SB-612111 is a novel and potent opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). SB-612111 exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. SB-612111 effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model .
|
-
- HY-18617
-
|
Opioid Receptor
|
Neurological Disease
Inflammation/Immunology
|
rel-SB-612111 hydrochloride is a novel and potent human opiate receptor-like orphan receptor (ORL-1) antagonist with a high affinity for hORL-1 (Ki=0.33 nM). rel-SB-612111 hydrochloride exhibits selectivity for μ-, κ- and δ-receptors with Ki values of 57.6 nM, 160.5 nM and 2109 nM, respecticely. rel-SB-612111 hydrochloride effectively antagonizes the pronociceptive action of Nociceptin (HY-P0183) in an acute pain model .
|
-
- HY-W250309
-
|
Biochemical Assay Reagents
|
Others
|
Pentaerythritol tetra(3-mercaptopropionate)It is a class of organic compounds containing both pentaerythritol and mercaptopropionate groups. It is commonly used as a stabilizer and crosslinking agent in various chemical and industrial applications. Pentaerythritol tetra(3-mercaptopropionate)Has a variety of properties that make it suitable for these applications, including the ability to increase the mechanical strength, thermal stability and weatherability of polymers and coatings. Additionally, it can be used as a feedstock for the production of other specialty chemicals and materials.
|
-
- HY-151766
-
|
ADC Linker
|
Others
|
DACN(Tos,Suc-OH) is a click chemistry reagent containing a cycloalkyne group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. Such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes have served for reliable molecular conjugation in a broad range of fields. The nitrogens are used as connection points for a variety of functional units. DACNs possess high thermal and chemical stability along with comparable click reactivity .
|
-
- HY-P5704
-
|
Bacterial
|
Infection
|
K11 is an antimicrobial peptide. K11 is active against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL), and inhibits bacterial biofilm formation. K11 can act synergistically with antibiotics (Chloramphenicol (HY-B0239), Meropenem (HY-13678), Rifampicin (HY-B0272), etc.) against drug-resistant K. pneumoniae. K11 has high thermal and wide pH stability .
|
-
- HY-161321
-
|
Phosphatase
Insulin Receptor
Akt
|
Metabolic Disease
|
PTP1B-IN-24 (Compound 9) is a reversible PTP1B inhibitor with an IC50 value of 1.4 μM, and PTP1B-IN-24 can enhance the thermal stability of PTP1B. PTP1B-IN-24 can restore PA- (HY-N0830) induced insulin resistance by increasing the phosphorylation levels of IRS1 and AKT .
|
-
- HY-19745
-
|
PD-1/PD-L1
Apoptosis
|
Cancer
|
BMS-202 is a potent and nonpeptidic PD-1/PD-L1 complex inhibitor with an IC50 of 18 nM and a KD of 8 μM. BMS-202 binds to PD-L1 and blocks human PD-1/PD-L1 interaction. BMS-202 has antitumor activity .
|
-
- HY-12914
-
|
TRP Channel
|
Neurological Disease
Inflammation/Immunology
|
V116517 is a potent, orally active transient receptor potential vanilloid (TRPV1) antagonist. V116517 shows potent activity in inhibiting both capsaicin (CAP)- and acid (pH 5)-induced currents in rat DRG neurons expressing native TRPV (IC50=423.2 nM for CAP; IC50=180.3 nM for acid). V116517 can be used for the research of pain .
|
-
- HY-131445A
-
|
Others
|
Metabolic Disease
Inflammation/Immunology
|
SS-RJW100 is a enantiomer of RJW100, which is a racemic agonist of nuclear receptor liver receptor homolog 1 (LRH-1) and steroidogenic factor 1 (SF-1). SS-RJW100 promotes recruitment of coregulator protein fragments in vitro, recruits the transcriptional intermediary factor 2 (Tif2) coactivator to LRH-1. SS-RJW100 diminishes LRH-1 allosteric activation networks, shows poor thermal stability .
|
-
- HY-D1189
-
Lucifer Yellow 3-amino-D-alanine
|
Fluorescent Dye
|
Others
|
YADA (Lucifer Yellow 3-amino-D-alanine) is a conjugate of the fluorescent dyes Lucifer yellow and D-alanine, which is a green-yellow fluorescent dye. YADA is suitable for labeling peptidoglycans in living bacteria that can be incorporated into the cell wall where they are being synthesized. YADA has a large Stokes shift and a wide emission spectrum, allowing excitation through a purple light source and detection using a green filter. YADA showed good water solubility, light stability and thermal stability.
|
-
- HY-125865
-
|
Casein Kinase
Endogenous Metabolite
|
Others
|
Casein is a phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties, including mechanical properties, water resistance, thermal stability, and barrier properties. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .
|
-
- HY-161071
-
|
Others
|
Infection
Cancer
|
Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1 .
|
-
- HY-W250127
-
Terephthalic acid disodium salt
|
Biochemical Assay Reagents
|
Others
|
Disodium terephthalate belongs to the class of organic salts. It is commonly used as a catalyst or intermediate in the production of a variety of industrial and consumer products, including polyethylene terephthalate (PET) plastics, polyester fibers and films. Disodium terephthalate has excellent thermal stability, chemical resistance and mechanical properties, making it ideal for high performance applications. Additionally, it is non-toxic, non-flammable and environmentally friendly, making it an attractive alternative to other petroleum-based chemicals. In the food and pharmaceutical industries, Disodium terephthalate is used as a pH regulator and buffer. It is generally considered safe for use in food and pharmaceutical applications by regulatory agencies such as the FDA.
|
-
- HY-W250308
-
Epsilon-polylysine; ε-Polylysine; ε-PL
|
Bacterial
|
Others
|
Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
|
-
- HY-110150
-
UNC3230
5 Publications Verification
|
Others
|
Inflammation/Immunology
Cancer
|
UNC3230 is a potent, selective and ATP-competitive PIP5K1C inhibitor with an IC50 of ~41 nM. UNC3230 also inhibits PIP4K2C and does not inhibit any of the other lipid kinases that regulate phosphoinositide levels. UNC3230 has antinociceptive and anticancer effects .
|
-
- HY-P1319
-
|
Opioid Receptor
|
Inflammation/Immunology
|
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo .
|
-
- HY-P1319A
-
|
Opioid Receptor
|
Inflammation/Immunology
|
Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) TFA is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-W248115
-
|
Fluorescent Dyes/Probes
|
Pyrromethene 597 is a BODIPY laser dye. Pyrromethene 597 displays wide tuning range of lasing wavelengths and high photostability. Pyrromethene 597 can be used as a thermal probe .
|
-
- HY-D1915
-
|
Fluorescent Dyes/Probes
|
ATTO 390 is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy.
|
-
- HY-D1305
-
|
Fluorescent Dyes/Probes
|
ATTO 488 carboxylic acid is a new fluorescent label based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 carboxylic acid is a carboxylic acid derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D1917
-
|
Fluorescent Dyes/Probes
|
ATTO 390 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 390 NHS ester is an NHS ester derivative of ATTO 390 that can be used to label proteins or antibodies.
|
-
- HY-D1929
-
|
Fluorescent Dyes/Probes
|
ATTO 594 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 594 NHS ester is an NHS ester derivative of ATTO 594 that can be used to label proteins or antibodies.
|
-
- HY-D1932
-
|
Fluorescent Dyes/Probes
|
ATTO 590 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 NHS ester is an NHS ester derivative of ATTO 590 that can be used to label proteins or antibodies.
|
-
- HY-D1933
-
|
Fluorescent Dyes/Probes
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
- HY-D1935
-
|
Fluorescent Dyes/Probes
|
ATTO 465 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 NHS ester is an NHS ester derivative of ATTO 465 that can be used to label proteins or antibodies.
|
-
- HY-D1939
-
|
Fluorescent Dyes/Probes
|
ATTO 465 amine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 465 amine is an amine derivative of ATTO 465 and can be used to label proteins or antibodies.
|
-
- HY-D1946
-
|
Fluorescent Dyes/Probes
|
ATTO 590 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 alkyne is an alkyne derivative of ATTO 590 and can be used to label proteins or antibodies.
|
-
- HY-D1957
-
|
Fluorescent Dyes/Probes
|
ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
|
-
- HY-D1959
-
|
Fluorescent Dyes/Probes
|
ATTO 565 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 NHS ester is an NHS ester derivative of ATTO 565 that can be used to label proteins or antibodies.
|
-
- HY-D1961
-
|
Fluorescent Dyes/Probes
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D1993
-
|
Fluorescent Dyes/Probes
|
ATTO 647 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 647 NHS ester is an NHS ester derivative of ATTO 647 that can be used to label proteins or antibodies.
|
-
- HY-D1999
-
|
Fluorescent Dyes/Probes
|
ATTO 665 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 665 NHS ester is an NHS ester derivative of ATTO 665 that can be used to label proteins or antibodies.
|
-
- HY-D2001
-
|
Fluorescent Dyes/Probes
|
ATTO 488 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 NHS ester is an NHS ester derivative of ATTO 488 that can be used to label proteins or antibodies.
|
-
- HY-D2002
-
|
Fluorescent Dyes/Probes
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2014
-
|
Fluorescent Dyes/Probes
|
ATTO 565 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 alkyne is an alkyne derivative of ATTO 565 and can be used to label proteins or antibodies.
|
-
- HY-D2015
-
|
Fluorescent Dyes/Probes
|
ATTO 488 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 alkyne is an alkyne derivative of ATTO 488 and can be used to label proteins or antibodies.
|
-
- HY-153524
-
|
Fluorescent Dyes/Probes
|
ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.
|
-
- HY-D2016
-
|
Fluorescent Dyes/Probes
|
ATTO 565 cadaverine is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 cadaverine is a cadaverine derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D2019
-
|
Fluorescent Dyes/Probes
|
ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
|
-
- HY-D2021
-
|
Fluorescent Dyes/Probes
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
- HY-D2026
-
|
Fluorescent Dyes/Probes
|
ATTO 514 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 NHS ester is an NHS ester derivative of ATTO 514 that can be used to label proteins or antibodies.
|
-
- HY-D2035
-
|
Fluorescent Dyes/Probes
|
ATTO 514 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 514 alkyne is an alkyne derivative of ATTO 514 and can be used to label proteins or antibodies.
|
-
- HY-D2038
-
|
Fluorescent Dyes/Probes
|
ATTO 550 alkyne is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 alkyne is an alkyne derivative of ATTO 550 and can be used to label proteins or antibodies.
|
-
- HY-D2046
-
|
Fluorescent Dyes/Probes
|
ATTO 532 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 NHS ester is an NHS ester derivative of ATTO 532 that can be used to label proteins or antibodies.
|
-
- HY-D2047
-
|
Fluorescent Dyes/Probes
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D2052
-
|
Fluorescent Dyes/Probes
|
ATTO 532 iodacetamid is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 iodacetamid is an iodoacetamide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D2058
-
|
Fluorescent Dyes/Probes
|
ATTO 700 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 NHS ester is an NHS ester derivative of ATTO 700 that can be used to label proteins or antibodies.
|
-
- HY-D2059
-
|
Fluorescent Dyes/Probes
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
- HY-D2062
-
|
Fluorescent Dyes/Probes
|
ATTO 740 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 NHS ester is an NHS ester derivative of ATTO 740 that can be used to label proteins or antibodies.
|
-
- HY-D2063
-
|
Fluorescent Dyes/Probes
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
- HY-D2073
-
|
Fluorescent Dyes/Probes
|
ATTO 680 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 NHS ester is an NHS ester derivative of ATTO 680 that can be used to label proteins or antibodies.
|
-
- HY-D2074
-
|
Fluorescent Dyes/Probes
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
-
- HY-D1189
-
Lucifer Yellow 3-amino-D-alanine
|
Fluorescent Dyes/Probes
|
YADA (Lucifer Yellow 3-amino-D-alanine) is a conjugate of the fluorescent dyes Lucifer yellow and D-alanine, which is a green-yellow fluorescent dye. YADA is suitable for labeling peptidoglycans in living bacteria that can be incorporated into the cell wall where they are being synthesized. YADA has a large Stokes shift and a wide emission spectrum, allowing excitation through a purple light source and detection using a green filter. YADA showed good water solubility, light stability and thermal stability.
|
Cat. No. |
Product Name |
Type |
-
- HY-D0877
-
|
Biochemical Assay Reagents
|
TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH) .
|
-
- HY-P2729
-
EC 3.4.21.14
|
Biochemical Assay Reagents
|
Subtilisin, or rubinase, is a bacterial serine protease. Subtilisin can be used as a detergent additive with thermal stability, pH tolerance, and calcium dependent stability .
|
-
- HY-W073183
-
|
Biochemical Assay Reagents
|
Dibenzo-24-crown-8-ether is a phase transfer catalyst that can reduce H 2PtCl 6·6H 2O and FeCl 2·4H 2O in a thermal system to synthesize 17 nm monodispersed iron-platinum (FePt) alloy nanoparticles .
|
-
- HY-W011831
-
3-(Benzyldimethylammonio)propane-1-sulfonate; PDA
|
Surfactants
|
NDSB-256 is a non-stain remover sulfabetaine. NDSB-256 prevents protein aggregation and promotes denaturation of chemically and thermally denatured proteins .
|
-
- HY-W040263
-
TAPS Na
|
Buffer Reagents
|
TAPS sodium is a biological buffer that protects the structural integrity of lysozyme bacteria and prevents them from thermal denaturation at high temperatures. A pKa of 8.1 for TAPS results in half-maximal connexin channel activity .
|
-
- HY-W040201
-
3-[3-(Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
|
Surfactants
|
CHAPSO is a zwitterionic detergent that is thermally stable. CHAPSO is able to broaden the particle orientation distribution, enabling single-particle cryo-electron microscopy (cryo-EM) to produce isotropically uniform maps. CHAPSO can eliminate the directional bias of bacterial transcription complexes and help determine the structure of bacterial transcription complexes under cryo-electron microscopy .
|
-
- HY-W250309
-
|
Biochemical Assay Reagents
|
Pentaerythritol tetra(3-mercaptopropionate)It is a class of organic compounds containing both pentaerythritol and mercaptopropionate groups. It is commonly used as a stabilizer and crosslinking agent in various chemical and industrial applications. Pentaerythritol tetra(3-mercaptopropionate)Has a variety of properties that make it suitable for these applications, including the ability to increase the mechanical strength, thermal stability and weatherability of polymers and coatings. Additionally, it can be used as a feedstock for the production of other specialty chemicals and materials.
|
-
- HY-125865
-
|
Native Proteins
|
Casein is a phosphoprotein that can be separated into various electrophoretic components, such as α2-Casein, κ-Casein, β-casein, and γ-casein. Casein has also been blended and grafted with other polymers, cross-linkers, or monomers to improve its functional properties, including mechanical properties, water resistance, thermal stability, and barrier properties. Casein has various applications in the paper, leather, textile, and food industries, serving as coatings, adhesives, and packaging materials .
|
-
- HY-W250127
-
Terephthalic acid disodium salt
|
Biochemical Assay Reagents
|
Disodium terephthalate belongs to the class of organic salts. It is commonly used as a catalyst or intermediate in the production of a variety of industrial and consumer products, including polyethylene terephthalate (PET) plastics, polyester fibers and films. Disodium terephthalate has excellent thermal stability, chemical resistance and mechanical properties, making it ideal for high performance applications. Additionally, it is non-toxic, non-flammable and environmentally friendly, making it an attractive alternative to other petroleum-based chemicals. In the food and pharmaceutical industries, Disodium terephthalate is used as a pH regulator and buffer. It is generally considered safe for use in food and pharmaceutical applications by regulatory agencies such as the FDA.
|
-
- HY-W250308
-
Epsilon-polylysine; ε-Polylysine; ε-PL
|
Biochemical Assay Reagents
|
Epsilon-polylysine is an antimicrobial peptide that can be produced by bacteria such as Streptomyces. Epsilon-polylysine inhibits the growth of microorganisms such as bacteria, yeasts and molds and is therefore often used as a green food additive and preservative in various food and beverage products. Epsilon-polylysine has a variety of properties, including thermal stability, resistance to acidic conditions, and broad-spectrum antimicrobial activity. Epsilon-polylysine can be loaded on other materials to form nanoparticles or form nanofiber membranes for targeted delivery to exert sustained antibacterial efficacy. Epsilon-polylysine is also used as a liposome stabilizer .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P5874
-
|
Calcium Channel
|
Inflammation/Immunology
|
Myr-TAT-CBD3 is CRMP2-CaV2.2 interaction inhibitor. Myr-tat-CBD3 can significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal hypersensitivity induced in a rat model of postoperative pain. Myr-TAT-CBD3 can be used to study inflammation and postoperative pain .
|
-
- HY-P3856
-
|
Peptides
|
Neurological Disease
|
Endokinin C is a peptide component of endokinin. Endokinin C works as a neurotransmitter or modulator in the pain system. Pretreatment with endokinin C prevents induction of scratching behavior and thermal hyperalgesia of endokinin A/B in mice .
|
-
- HY-P5802
-
|
Calcium Channel
|
Neurological Disease
|
ω-Conotoxin FVIA is an N-type Ca 2+channel (Ca v 2.2)
inhibitor. ω-Conotoxin FVIA reduces mechanical and thermal pain abnormalities
in a rat model of caudal nerve injury. ω-Conotoxin FVIA can be used in the
study of highly effective pain relievers with low side effects
.
|
-
- HY-P5704
-
|
Bacterial
|
Infection
|
K11 is an antimicrobial peptide. K11 is active against MDR/XDR K. pneumoniae isolates (MIC: 8-512 μg/mL), and inhibits bacterial biofilm formation. K11 can act synergistically with antibiotics (Chloramphenicol (HY-B0239), Meropenem (HY-13678), Rifampicin (HY-B0272), etc.) against drug-resistant K. pneumoniae. K11 has high thermal and wide pH stability .
|
-
- HY-P1319
-
|
Opioid Receptor
|
Inflammation/Immunology
|
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo .
|
-
- HY-P1319A
-
|
Opioid Receptor
|
Inflammation/Immunology
|
Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) TFA is a potent ORL1 (NOP) receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-B0352AS
-
|
(S)-Mirtazapine-d3 is a deuterium labeled (S)-Mirtazapine. (S)-Mirtazapine is a S(+)-enantiomer of Mirtazapine with pronociceptive properties in an animal model of acute thermal nociception.(S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist. (S)-Mirtazapine is metabolized by CYP2D6 and CYP1A2[1].
|
-
-
- HY-N6600S
-
|
Octadecane-d38 is the deuterium labeled Octadecane[1]. Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material[2].
|
-
-
- HY-N9929S
-
|
Docosane-d46 is the deuterium labeled Docosane[1]. Docosane, a straight chain alkane, can be used to synthesize structural composites with thermal energy storage/release capability[2][3].
|
-
-
- HY-B0352BS
-
|
(R)-Mirtazapine-d3 is a deuterium labeled (R)-Mirtazapine. (R)-Mirtazapine is a R(−)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4[1].
|
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent: